Minimal persistent inflammation in Japanese cedar pollinosis and a prophylactic effect of intranasal corticosteroids
نویسندگان
چکیده
Background Low doses of allergen exposure can cause an activation of inflammatory cells in nasal mucosa without an onset of nasal symptoms, called MPI (minimal persistent inflammation). MPI contributes to hyperreactivity and subsequently onset of the full-scale symptom. However, little is known whether MPI is present in JCP (Japanese cedar pollinosis). In addition, a prophylactic effect of intranasal corticosteroids on MPI in JCP has not been investigated.
منابع مشابه
Effect of intranasal corticosteroid on pre-onset activation of eosinophils and mast cells in experimental Japanese cedar pollinosis.
BACKGROUND Minimal persistent inflammation (MPI) contributes to hyperreactivity in allergic rhinitis. However, little is known regarding whether pre-onset activation of eosinophils and mast cells is present or not in Japanese cedar pollinosis (JCP). Furthermore, a prophylactic effect of intranasal corticosteroids on such MPI in JCP has not been investigated. METHODS We designed a double-blind...
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